Table 3.
Meta-analysis of haplotype GTCT on SNPs 6, 7, 13, and 15 across five samples
Sample | N | case | control | OR | Z statistic | P-value | Adjusted P-value |
---|---|---|---|---|---|---|---|
Stage 1 | 1316 | 0.235 | 0.163 | 1.56 | 4.21 | 0.000025 | 0.0045 (single-stage) |
NECS | 738 | 0.239 | 0.163 | 1.60 | 3.05 | 0.0023 | |
French | 1103 | 0.208 | 0.207 | 1.01 | 0.074 | 0.94 | |
SICS | 905 | 0.175 | 0.157 | 1.14 | 1.05 | 0.29 | |
Ashkenazi | 702 | 0.114 | 0.139 | 0.80 | −1.40 | 0.16 | |
Full meta-analysis | 1.18 | 3.37 | 0.00075 | 0.037 (two-stage) |