Skip to main content
. Author manuscript; available in PMC: 2012 Nov 10.
Published in final edited form as: Nature. 2012 Apr 8;485(7397):264–268. doi: 10.1038/nature11013

Figure 4. HNRPA2B1 regulates growth rate.

Figure 4

a, Whole genome expression levels across five breast cancer cell lines (MCF7, MDA-MB-231, HS578T, BT-549 and T47D) were correlated against their doubling times17. The resulting values, ranging from −1 to 1, were analyzed by TEISER to probe the enrichment/depletion pattern of transcripts carrying sRSM1. b, The growth of HNRPA2B1 siRNA-transfected samples was compared to those of mock-transfected controls. For each time-point, the number of cells in four independent samples was counted in duplicates (n=8), yielding an estimated growth-rate (α). Shown are the average log-ratios, their standard deviation at each time-point, and the statistical significance of the observed difference in growth-rate.