Figure 2. Natural and synthetic nonhydrolyzable aminoacyl-adenylate analogs and the corresponding aminoacyl-adenylates that are mimicked by these molecules.
Also shown are the synthetic aspartyl-tRNA synthetase inhibitor DSA and the chemical structure of the unprocessed McC.
AspRS: Aspartyl-adenylate synthesized by aspartyl-tRNA synthetase; DSA: Aspartyl sulfamoyl adenylate; LeuRS: Leucyl-adenylate synthesized by leucil-tRNA synthetase; McC: Microcin C; SerRS: Seryl-adenylate synthesized by seryl-tRNA synthetase.