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. 2011 Dec 7;42(3):483–499. doi: 10.1007/s10519-011-9522-x

Table 4.

Power to detect AxE in the presence of A × C, and power to detect A × C in the presence of A × E when data is simulated under Purcell’s bivariate moderation model

rGE G × E effect ACE–A × E–A × C
Power to detect A × E A × C
0.3 None 0.05 0.05
Small 0.84 0.05
Medium 0.87 0.05
Large 0.91 0.05
0.4 None 0.05 0.05
Small 0.66 0.05
Medium 0.70 0.05
Large 0.84 0.05
0.5 None 0.06 0.06
Small 0.51 0.20
Medium 0.53 0.45
Large 0.95 0.65

rGE Size of the genotype by environment correlation due to shared genes between the moderator and the phenotypic variable