. Author manuscript; available in PMC: 2013 Mar 14.

Published in final edited form as: J Am Chem Soc. 2012 Feb 29;134(10):4709–4720. doi: 10.1021/ja209809t

Table 1.

The genes required for austinol/dehydroaustinol biosynthesis in A. nidulans

ORFs		Homologs
Gene	Predicted size (aa)	Match from BLAST search at NCBI (accession no.)	Identity/s imilarity (%)
AN8379.4 (ausB)	745	cyclopentadecanone 1,2-monooxygenase [Pseudomonas sp. HI-70] (BAE93346)	37/54
AN8381.4 (ausC)	638	cyclododecanone monooxygenase [Rhodococcus ruber] (AAL14233)	43/56
AN8383.4 (ausA)	2476	methylorcinaldehyde synthase [Acremonium strictum] (CAN87161)	32/51
AN8384.4 (ausD)	282	Hypothetical protein
AN9246.4 (ausE)	298	Fumonisin C-5 hydroxylase Fum3p [Gibberella moniliformis] (AAG27131)	34/52
AN9247.4 (ausF)	177	Hypothetical protein
AN9248.4 (ausG)	529	P450 monooxygenase [Sphaceloma manihoticola] (CAP07651)	40/59
AN9249.4 (ausH)	174	Hypothetical protein
AN9253.4 (ausI)	501	P450 monooxygenase [Sphaceloma manihoticola] (CAP07653)	32/55
AN11214.4 (ausJ)	162	Hypothetical protein
AN11205.4 (ausK)	398	Norsolorinic acid reductase [Aspergillus parasiticus] (Q00258)	48/66
AN9257.4 (ausL)	204	Terpene cyclases pyr4 [Aspergillus fumigatus F37]¹³	32/55
AN11206.4 (ausM)	479	a. PaxM [Penicillium paxilli] (AAK11530) b. FAD-dependent monooxygenase pyr5 [Aspergillus fumigatus F37]¹³	a. 46/65 b. 42/58
AN9259.4 (ausN)	330	a. 4-hydroxybenzoate geranyltransferase [Lithospermum erythrorhizon] (BAB84122) b. Prenyltransferase pyr6 [Aspergillus fumigatus F37]¹³	a. 30/49 b. 30/46