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(b) NF1. Presence of two or more clinical features
| Family history of NF1 | Neurofibromas or plexiform neurofibromas |
|---|---|
| Six or more cafe-au-lait spots | Axillary or groin freckling |
| Lisch nodules | Skeletal abnormalities—tibial dysplasia or shin bone thinning |
| Optic glioma |
