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Nutlin-3 inhibits tumor growth in nude mice. (A) examples of tumors resulting from xenografted TIVE-KSHV cells in nude mice that were treated with daily IP injection of Nutlin-3 or placebo; (B) average tumor volumes from a total of 10 tumors in five Nutlin-3-treated mice and 10 tumors in placebo-treated mice over a period of 52 d. Treatment started on day 10 post-inoculation when average tumor size was about 0.2 cm3.
