Table 3.
Correlates of the E/A, e'/a' and E/e' ratios in stepwise regression by cohort
| Parameter | Transmitral E/A | Averaged TDI e'/a' | E/e' | |||
|---|---|---|---|---|---|---|
| FLEMENGHO | EPOGH | FLEMENGHO | EPOGH | FLEMENGHO | EPOGH | |
| R2 (%) | 67.5 | 65.9 | 73.6 | 71.2 | 49.6 | 46.2 |
| Adjusted R2 (%) | 67.3 | 65.4 | 73.4 | 70.6 | 49.0 | 45.1 |
| Partial regression coefficients | ||||||
| Female (0,1) | ||||||
| ß ± SE | 0.064 ± 0.025* | 0.084 ± 0.039* | 0.62 ± 0.15‡ | 0.37 ± 0.19* | ||
| Partial r2 (%) | 0.22 | 0.29 | 1.4 | 0.44 | ||
| Age (+10 years) |
||||||
| ß ± SE | -0.23 ± 0.008‡ | -0.24 ± 0.012‡ | -0.32 ± 0.009‡ | -0.28 ± 0.015‡ | 0.38 ± 0.048‡ | 0.50 ± 0.068‡ |
| Partial r2 (%) | 53.6 | 51.4 | 61.1 | 54.4 | 33.6 | 35.4 |
| BMI (+1 kg/m2) |
||||||
| ß ± SE | -0.017 ± 0.003‡ | -0.011 ± 0.00‡ | -0.031 ± 0.003‡ | -0.026 ± 0.004‡ | 0.093 ± 0.015‡ | 0.078 ± 0.017‡ |
| Partial r2 (%) | 2.5 | 0.78 | 6.8 | 6.5 | 3.1 | 2.3 |
| HR (+10 beats/minute) | ||||||
| ß ± SE | -0.13 ± 0.011‡ | -0.13 ± 0.014‡ | -0.11 ± 0.013‡ | -0.13 ± 0.017‡ | -0.16 ± 0.063† | |
| Partial r2 (%) | 9.5 | 8.6 | 3.2 | 4.1 | 0.46 | |
| SBP (+10 mmHg) | ||||||
| ß ± SE | 0.025 ± 0.008† | 0.030 ± 0.012* | 0.044 ± 0.010‡ | 0.36 ± 0.045‡ | 0.36 ± 0.068‡ | |
| Partial r2 (%) | 0.43 | 0.43 | 0.7 | 5.1 | 4.2 | |
| DBP (+10 mmHg) | ||||||
| ß ± SE | -0.075 ± 0.013‡ | -0.079 ± 0.019‡ | -0.12 ± 0.016‡ | -0.071 ± 0.017‡ | -0.21 ± 0.076† | -0.27 ± 0.10† |
| Partial r2 (%) | 0.97 | 1.5 | 1.7 | 1.7 | 0.70 | 0.82 |
| LVMI (+10 g/m2) | ||||||
| ß ± SE | -0.025 ± 0.011* | 0.16 ± 0.032‡ | 0.13 ± 0.049† | |||
| Partial r2 (%) | 0.67 | 1.4 | 0.49 | |||
| LV length (+1 cm) | ||||||
| ß ± SE | -0.53 ± 0.10‡ | -0.45 ± 0.13‡ | ||||
| Partial r2 (%) | 3.8 | 1.8 | ||||
Values are mutually adjusted partial regression coefficients ± SE. BMI, body mass index; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; LVMI, left ventricle mass index. Significance of the partial regression coefficient: * P < 0.05, †P < 0.01, and ‡P < 0.001. There were no differences between the partial regression coefficients in two studies (P ≥ 0.10)