Table 1.

Distribution of sequences across different classes in training and test data combined together

Class	Sub-classes	Number of sequences
1 Oxidoreductases	1.1, 1.2, 1.3, 1.4, 1.5, 1.10, 1.16	986
2 Transferases	2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8	734
3 Hydrolases	3.1, 3.2, 3.3, 3.4, 3.5, 3.6, 3.7, 3.8, 3.11	674
4 Lyases	4.1, 4.2, 4.3, 4.4, 4.6, 4.99	828
5 Isomerases	5.1, 5.2, 5.3, 5.4, 5.5	664
6 Ligases	6.1, 6.2, 6.3, 6.4	845

The sequences extracted from SWISS-PROT enzyme database are spread over a total of 40 sub-classes. Sequences have been extracted from the sub-classes having the largest bank of sequences. The number of sequences shown represent sequences with 100% reduced identity.