Table 2.
Concentration of total hCG and hyperglycosylated hCG (hCG-H) in 496 serum samples from 310 women with term pregnancies measured using the Siemens Immulite 1000 total hCG assay
| Gestation age (weeks since start of menstrual period) | N | Median Total hCG ng/ml | Range Total hCG ng/ml (variation) | Median hCG-H ng/ml | Range hCG-H ng/ml (variation) | hCG-H % |
|---|---|---|---|---|---|---|
| 3-weeks (3 weeks 0 days - 6 days) | n = 42 | 0.26 (16 of 42 < 0.1 ng/ml) | 0.04 - 5.5 | 0.20(16 of 42 < 0.1 ng/ml) | 0.01 - 6.45 (645X) | 87% |
| 4 weeks | n = 42 | 3.4 | 0.21 - 173 (824X) | 2.5 | 0.18 - 160 (888X) | 51% |
| 5 weeks | n = 67 | 65 | 1.86 - 1308 (704X) | 8.6 | 0.96 - 698 (731X) | 43% |
| 6-weeks | n = 29 | 252 | 3.80 - 855 (225X) | 86 | 0.76 - 629 (827X) | 36% |
| 7 weeks | n = 30 | 3,278 | 203 - 7,766 (38X) | 359 | 27 - 931 (34X) | 16% |
| 8 weeks | n = 33 | 4,331 | 1,064 - 10,057 (9.4X) | 386 | 67 - 1050 (15.6X) | 7.0% |
| 9 weeks | n = 24 | 5,832 | 1,031 - 11,586 (11.2X) | 430 | 102 - 1158 (11.3X) | 5.1% |
| 10 weeks | n = 20 | 10,352 | 1,952 - 19,958 (10.2X) | 521 | 188 - 1855 (9.9X) | 4.3% |
| 11 - 13 weeks | n = 41 | 5,953 | 1,440 - 15,318 (10.6X) | 137 | 24 - 330 (13.7X) | 2.3% |
| 14 - 17 weeks | n = 57 | 2,934 | 311 - 4,757 (15.2X) | 26 | 6.7 - 129 (19.3X) | 1.3% |
| 18 - 26-weeks | n = 62 | 1,931 | 210 - 6,223 (30.3X) | 15.8 | 5.3 - 95 (17.9X) | 0.65% |
| 27 - 40 weeks | n = 49 | 1,911 | 184 - 8,530 (46.4X) | 2.95 | 0.3 - 12.2 (40.6X) | 0.14% |
Data from 50 pregnancies that failed due to miscarriage were excluded from this table. Pregnancies which failed to implant in early pregnancy (total hCG < 0.1 ng/ml) are indicated in parenthesis