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. Author manuscript; available in PMC: 2012 May 14.
Published in final edited form as: Mol Cell Neurosci. 2010 Jan 18;43(4):353–362. doi: 10.1016/j.mcn.2010.01.002

Figure 2.

Figure 2

Lrrc3b expression is altered in the CNGA2 (−/0) olfactory epithelium (A) Schematic diagram of the predicted Lrrc3b protein. The signal peptide (SP), LRR domain and transmembrane domain (TM) are indicated along with the corresponding amino acid positions. (B) Northern analysis of two independent OE RNA samples from wild type and CNGA2(−/0) animals probed for Lrrc3b message. Lrrc3b is more abundant in wild type tissue than in CNGA2(−/0) OE. The actin mRNA control reveals similar gel loading and RNA quality for each lane. (C) In situ hybridization with a Lrrc3b antisense probe on wild type and CNGA2(−/0) OE in adult mice. scale bar = 50 microns (D) Higher magnification image of Lrrc3b in situ signal confirms the restricted expression and variable levels in ORNs. scale bar = 25 microns.