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. Author manuscript; available in PMC: 2013 Apr 27.
Published in final edited form as: Cell. 2012 Apr 27;149(3):515–524. doi: 10.1016/j.cell.2012.04.005

Figure 2.

Figure 2

Network motifs for cell fate switches.

(A) A coherent feedforward loop both directly and indirectly inhibits the cell cycle regulator E2F1 in granulopoiesis.

(B) A mutual negative feedback loop contributes to bistability between myeloid precursors and granulocytes.

(C) A positive feedback loop enforces lineage commitment of nematode “2 degrees” vulval cells.