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. Author manuscript; available in PMC: 2013 Apr 27.
Published in final edited form as: Cell. 2012 Apr 27;149(3):515–524. doi: 10.1016/j.cell.2012.04.005

Figure 5.

Figure 5

miRNA-target interaction produces non-linear target protein output. Below a certain threshold of target mRNA production, the target is strongly repressed (pink). Above the threshold, repression is weaker and the target can exert competitive “sponge”-like effects (blue). The position of the threshold depends on miRNA concentration. Cartooned from (Mukherji et al., 2011) data.