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. 2012 Feb;60(2):97–109. doi: 10.1369/0022155411433066

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© The Histochemical Society 2012

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Figure 4. — Global analysis: volume fractions of elastin, smooth muscle cell actin (SMCA), and collagen type I. (A) A significant decrease in elastin volume fraction at day 7 and day 28 relative to day 0 was observed in the elastase group only. (B) SMCA volume fraction decreased significantly from day 0 to day 7 and returned at day 28, although still significantly suppressed relative to day 0, in both groups. (C) The largest decrease in adventitial collagen type I volume fraction occurred from day 0 to day 7 and remained significantly suppressed at day 28, relative to day 0, in both groups. Mean ± SEM, N=20, n=4 per group.