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Structural analysis: elastin thickness and non-adventitial wall thickness. (A) Elastin thickness decreased across all time points in the elastase group. The overall decrease in elastin thickness from day 0 to day 28 was larger in the elastase group (48.9%) than in the heat-inactivated elastase group (3.8%). (B) Non-adventitial wall thickness increased over time, with the largest increase (66.4%) occurring from day 7 to day 28 in the elastase group. Mean ± SEM, N=20, n=4 per group.
