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Functional fluorescent MutL and MutS co-localize on DNA mismatches. (A) Mutation frequency of mutL mutS deletion strain expressing fluorescently labeled MutS and MutL. Fluorescent images (taken with yellow and blue filters) and overlay image of mutH strain expressing (B) YFP-MutL and CFP-MutS or (C) YFP-MutS and CFP-MutL. Mean and standard error of the mean are presented in panel A. RifR stands for rifampicin resistant.
