Figure 3.
Insulin effect on estradiol production by macaque follicles in vitro. Estradiol levels for no-grow (panel A), slow-grow (panel B), and fast-grow (panel C) follicles from young adult animals (n = 3) during culture in media containing FSH and either low- or high-dose insulin, without LH supplementation at day 30. Significant differences over time (lowercase) or between the insulin dosage groups (uppercase) are indicated by different letters (P < 0.05). Data are presented as the mean ± s.e.m.