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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Mult Scler. 2011 Oct 13;17(12):1405–1411. doi: 10.1177/1352458511425366

Table 2.

Dose-escalation scheme for the safety/tolerability trials of cholecalciferol and MS

Cholecalciferol (IU/d)
Kimball, 2007 Burton, 2010
Study Weeks
1–2 0 0
3–4 4,000 4,000
5–10 8,000 10,000
11–16 16,000 16,000
17–22 32,000 32,000
23–28 40,000 40,000
29–40 na 10,000
41–48 na 4,000
49–42 na 0