Skip to main content
. Author manuscript; available in PMC: 2013 Apr 6.
Published in final edited form as: Org Lett. 2012 Mar 27;14(7):1934–1937. doi: 10.1021/ol300632p

Table 1.

Asymmetric alkylation of indole 5 by Z-vinyldiazoacetate 1a

graphic file with name nihms367002u2.jpg
entry catalyst yield (%) ee (%)a
1 Rh2(S-PTAD)4 88 48
2 Rh2(S-DOSP)4 93 −10
3 Rh2(S-TISP)4 84 −26
4 Rh2(S-biTISP)2 90 0
a

Negative value indicates opposite asymmetric induction.