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Summary of histone PTMs variations at the IDDM1 locus between T1D patients and normals (monocytes)
The definitions of the enriched region, hyper-peak and hypo-peaks are provided under “Experimental Procedures.” IDDM1 locus spans from 32381849 to 33606563 on chromosome 6, based on human NCBI build 36. Computation indicates the key variations in chromatin marks histone H3K9Ac and H4K16Ac at key loci, but not other marks in monocytes of TID versus normals (in the IDDM1 locus).
