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SPR competition assay sensorgrams. A, binding of TRPM335–124, TRPM335–124/Ca2+-CaM and TRPM335–124/Ca2+-S100A1 to S100A1. RU, relative units. B, binding of TRPM335–124, TRPM335–124/Ca2+-CaM, and TRPM335–124/Ca2+-S100A1 to CaM. C, binding of TRPM3291–382, TRPM3291–382/Ca2+-CaM, and TRPM3291–382/Ca2+-S100A1 to S100A1. D, binding of TRPM3291–382, TRPM3291–382/Ca2+-CaM, and TRPM3291–382/Ca2+-S100A1 to CaM.
