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. 2012 Mar 21;287(20):16256–16266. doi: 10.1074/jbc.M112.348250

FIGURE 2.

FIGURE 2.

Domain architecture of Vps30 and sequence alignment with homologues. A, domain architecture of Vps30. B, sequence alignment of the C-terminal region of Vps30/Beclin 1 homologues. Perfectly conserved residues are shaded black, and residues conserved as hydrophobic are shaded gray. The secondary structural elements of BARA are shown above the alignment. HsBec1, Homo sapiens Beclin 1; At, Arabidopsis thaliana; Dm, Drosophila melanogaster.