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. 2012 Mar 20;287(20):16699–16708. doi: 10.1074/jbc.M111.315333

FIGURE 1.

FIGURE 1.

CS exposure results in decreased FUT8 enzyme activity. A, CS specifically decreased FUT8 enzyme activity. In addition to FUT8, other N-glycosyltransferases (β1,4-N-acetylglucosaminyltransferases III (GnT-III) and IV (GnT-IV) and β1,6-N-acetylglucosaminyltransferase V (GnT-V)) were compared in all 2-week CS-exposed mice and their controls. B, the decline in FUT8 enzyme activity in the lung tissues persisted for the entire CS exposure period. FUT8 enzyme activities in all CS-exposed mice at each time point (2 weeks, 2 months, and 3 months) are shown. C, the reduction of gene expression levels of Fut8 caused by a 2-week CS exposure was much more significant in Fut8+/− mice. Data are the mean ± S.E. (n = 10). *, p < 0.05; **, p < 0.02; ***, p < 0.01 versus the matched groups connected with bars.