FIGURE 4.

Suction electrode recordings of rod light responses to graded series of in WT and Cav-1 KO mice. A, mean current traces in WT rods to flashes at intensities of 4, 17, 43, 160, 450, and 1122 photons μm⁻². The average dark current in WT rods was 14.1 ± 0.6 pA (n = 45). B, mean current traces from Cav-1 KO rods to the same flash intensities. The average dark current in Cav-1 KO rods was 12.5 ± 1.1 pA (n = 9), not significantly different from WT (p = 0.24, Student's t test). The flash sensitivity of the Cav-1 rods was 0.26 ± 0.03 pA/photon/μm² (n = 9), not significantly different (p = 0.20) from WT (0.31 ± 0.02 pA/photon/μm²; n = 45). For more details about suction electrode-determined parameters, see “Experimental Procedures” and supplemental Fig. 5.