Table 10. Changes in the abundance of UDP glucuronosyl transferase transcripts in diabetic animals.
| |
|
Fold change* |
Fold change* |
Fold change* |
|---|---|---|---|---|
| Gene symbol | Gene name | D vs N | D + mRAGE-Fc vs N | D + PHA666859 vs N |
| Ugt1a5 |
UDP glucuronosyltransferase 1 family, polypeptide A5 |
3.3 |
2 |
1.5 |
| Ugt1a10 |
UDP glucuronosyltransferase 1 family, polypeptide A10 |
3.3 |
2 |
1.5 |
| Ugt1a1 |
UDP glucuronosyltransferase 1 family, polypeptide A1 |
3.3 |
2 |
1.5 |
| Ugt1a9 |
UDP glucuronosyltransferase 1 family, polypeptide A9 |
3.3 |
2 |
1.5 |
| Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
3.3 |
2 |
1.5 |
| Ugt1a7c |
UDP glucuronosyltransferase 1 family, polypeptide A7C |
3.3 |
1.9 |
1.5 |
| Ugt1a6a |
UDP glucuronosyltransferase 1 family, polypeptide A6A |
3.3 |
2 |
1.5 |
| Ugt1a6b | UDP glucuronosyltransferase 1 family, polypeptide A6B | 3.1 | 2.1 | 1.5 |
*D=diabetic control, n=nondiabetic control, D+mRAGE-Fc=diabetic plus murine RAGE-Fc fusion protein, D+PHA666859=diabetic plus p38 MAPK inhibitor PHA666859.