Table 2. Comparison of transcript abundance changes obtained by two methods*.
| Gene | Fold-method I* | Gene | Fold-method I* | Gene | Fold-method II* | Gene | Fold-method II* |
|---|---|---|---|---|---|---|---|
| Crybb2 |
19.8 |
Tmem40 |
2.4 |
Rnu73a |
93.3 |
Pdlim1 |
3.7 |
| Cryba1 |
19.4 |
Crygc |
2.4 |
Lim2 |
75.7 |
Trim16 |
3.7 |
| Cryba4 |
18.3 |
Acta2 |
2.3 |
Wnt7a |
47.9 |
Lenep |
3.6 |
| Crygs |
18.2 |
Igfbp7 |
2.3 |
Pitx3 |
40.1 |
S100a6 |
3.6 |
| Cryaa |
17.9 |
Lyz2 |
2.3 |
Tmem40 |
38 |
Cd44 |
3.6 |
| Lim2 |
17.6 |
Vit |
2.3 |
Mip |
36 |
Gpd1 |
3.5 |
| Mip |
16.7 |
Tmem27 |
2.2 |
Wnt7b |
26.1 |
Cbr2 |
3.4 |
| Cryba2 |
16.4 |
Gsn |
2.2 |
Gja3 |
23.8 |
Nanos2 |
3.4 |
| Crybb1 |
15.1 |
C1qtnf5 |
2.2 |
Grifin |
23.7 |
Gpnmb |
3.4 |
| Bfsp2 |
10.7 |
Mfrp |
2.2 |
Cryba4 |
23.1 |
Gsta3 |
3.4 |
| Lgsn |
10.1 |
Igfbp7 |
2.1 |
Bfsp2 |
21 |
Ugt1a5 |
3.3 |
| Grifin |
9.8 |
Ucp2 |
2.1 |
Crybb2 |
20.3 |
Ugt1a10 |
3.3 |
| Crybb3 |
9.2 |
Rspo1 |
2.1 |
Crybb1 |
20.2 |
Ugt1a1 |
3.3 |
| Crybb3 |
8.9 |
Crygc |
2.1 |
Crygs |
20 |
Ugt1a9 |
3.3 |
| Dct |
7.2 |
Wnt7a |
2.1 |
Cryba1 |
19.8 |
Ugt1a2 |
3.3 |
| Cd24a |
6.7 |
Trpm1 |
2.1 |
Cryaa |
18.9 |
Bmper |
3.3 |
| Bfsp1 |
6.6 |
Npff |
2.1 |
Cryba2 |
18.5 |
Ugt1a7c |
3.3 |
| Lctl |
6.6 |
Krt15 |
2.1 |
Tyr |
18.5 |
Ugt1a6a |
3.2 |
| Cryab |
6.6 |
Selenbp1 |
2.1 |
Crybb3 |
16.3 |
1700093K21Ri |
3.2 |
| S100a4 |
4.9 |
Tspan10 |
2 |
Lctl |
14.5 |
1110017D15Ri |
3.1 |
| Ttr |
4.8 |
Mgst1 |
2 |
Cd24a |
10.7 |
Ugt1a6b |
3.1 |
| Mlana |
4.8 |
Tmem176a |
2 |
Mlana |
10.7 |
Cox8b |
3.1 |
| Gja3 |
4.6 |
Papss2 |
2 |
Dct |
9.8 |
Acta2 |
3.1 |
| Crygb |
4.5 |
Mlph |
2 |
Krt5 |
9.2 |
Pla2g2f |
3 |
| Rgr |
4.2 |
Gsta3 |
2 |
Sfrp1 |
7.8 |
Ahnak |
3 |
| Crygd |
3.9 |
Gsto1 |
2 |
Lrat |
6.8 |
Lix1 |
2.9 |
| Pmel |
3.9 |
Perp |
2 |
S100a4 |
6.4 |
Adamts4 |
2.8 |
| Sfrp1 |
3.9 |
Srd5a2 |
2 |
Ttr |
6.4 |
Ela1 |
2.7 |
| Egr1 |
3.6 |
Psca |
2 |
Mlph |
6.3 |
Angptl4 |
2.7 |
| Tyrp1 |
3.3 |
C1qtnf5 |
2 |
Rgr |
5.7 |
Galr2 |
2.6 |
| Aldh3a1 |
3.3 |
Mfrp |
2 |
Tgm1 |
5.6 |
Dock5 |
2.6 |
| Fabp5 |
3.2 |
Lgals1 |
1.9 |
Rpe65 |
5.5 |
Scel |
2.6 |
| Lenep |
3.2 |
Islr |
1.9 |
Emp1 |
5.3 |
Ppfibp2 |
2.6 |
| Gpnmb |
3.2 |
Penk |
1.9 |
Srd5a2 |
5.2 |
Pld5 |
2.6 |
| Gja8 |
3.2 |
Oca2 |
1.9 |
Slc6a20a |
5.2 |
Thbs1 |
2.5 |
| Serpina3n |
3.1 |
Aldh3a1 |
1.9 |
Fam46c |
5 |
Selenbp1 |
2.5 |
| Wnt7b | 2.9 | Ak1 | 1.9 | D21Rik | 4.8 | Ucp2 | 2.5 |
*The work-flow, Method I (BWA-ANOVA) and Method II (ELAND-SAM) are described in the Methods’ section. The numbers indicate fold changes between diabetic and nondiabetic controls as determined by two different algorithms.