Table 6. Relative levels of transcripts associated with inflammatory pathway in diabetic mice.
| |
|
Fold change* |
Fold change* |
Fold change* |
|---|---|---|---|---|
| Gene symbol | Gene name | D vs N | D + mRAGE-Fc vs N | D + PHA666859 vs N |
| C1qtnf5 |
C1q and tumor necrosis factor related protein 5 |
2.2 |
1.9 |
1.5 |
| CD44 |
CD44 antigen |
1.7 |
1.3 |
1.2 |
| Ltbp1 |
Latent transforming growth factor beta binding protein 1 |
1.6 |
1.4 |
1.4 |
| Islr |
Immunoglobulin superfamily containing leucine-rich repeat |
1.6 |
1.5 |
1.6 |
| Hspb1 |
Heat shock protein 1 |
1.6 |
1.6 |
1.2 |
| Ifitm1 |
Interferon induced transmembrane protein 1 |
1.5 |
1.4 |
1.3 |
| Bmp4 | Bone morphogenetic protein 4 | 1.5 | 1.6 | 1.5 |
*D=diabetic control, n=nondiabetic control, D+mRAGE-Fc=diabetic plus murine RAGE-Fc fusion protein, D+PHA666859=diabetic plus p38 MAPK inhibitor PHA666859.