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. 2012 May 14;7(5):e37159. doi: 10.1371/journal.pone.0037159

Table 5. List of up-regulated genes in CD90+CSCs as compared with CD90+NTSCs.

GeneId GeneSymbol Gene Name log2 ratio P value FDR Function
NM_130786 A1BG Alpha-1-B glycoprotein 4.645 0.026 0.032 Plasma glycoprotein
NM_001023587 ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.069 0.037 0.041 Drug efflux transporter
NM_001615 ACTG2 Actin, gamma 2, smooth muscle, enteric 6.495 0.001 0.002 Cell motility
NM_001633 AMBP Alpha-1-microglobulin/bikunin precursor 1.531 0.000 0.000 Precursor of urinary trypsin inhibitor and lipocalin transport protein
NM_001643 APOA2 Apolipoprotein A2 2.434 0.000 0.000 Stabilize high density lipoprotein (HDL) structure and HDL metabolism
NM_000041 APOE Apolipoprotein E 2.519 0.002 0.004 Lipoprotein catabolism, binding and internalization
NM_001645 APOC1 Apolipoprotein C1 1.601 0.000 0.000 Modulate lipoprotein interactions
NM_152547 BTNL9 Butyrophilin-like protein 9 precursor 1.693 0.000 0.000 Membrane-based protein with unknown function
NM_001855 COL15A1 Collagen, type XV, alpha 1 2.858 0.013 0.019 Structural protein
NM_001008540 CXCR4 Chemokine (C-X-C motif) receptor 4 2.663 0.000 0.000 Receptor specific for stromal cell-derived factor-1
NM_001135604 ESM1 Endothelial cell-specific molecule 1 2.590 0.018 0.024 Lung endothelial cell-leukocyte interactions and endothelium-dependent pathological disorders
NM_001442 FABP4 Fatty acid binding protein 4, adipocyte 2.183 0.000 0.000 Fatty acid uptake, transport, and metabolism
NM_004467 FGL1 Fibrinogen-like 1 2.832 0.000 0.000 Hepatocyte mitogenic activity, HCC development
NM_004484 GPC3 Glypican 3 2.686 0.026 0.032 Control of cell division and growth regulation
NR_002196 H19 H19, imprinted maternally expressed transcript (non-protein coding) 2.900 0.000 0.000 Tumor suppression
NM_000412 HRG Histidine-rich glycoprotein 1.713 0.031 0.036 Blood coagulation
NM_000599 IGFBP5 Insulin-like growth factor binding protein 5 2.992 0.000 0.000 Prolong the half-life of the IGFs and regulate the growth promoting effects of IGFs
NM_002215 ITIH1 Inter-alpha (globulin) inhibitor H1 2.536 0.018 0.024 Hyaluronan synthesis, binding and transport and stimulation of phagocytotic cells
NM_002217 ITIH3 Inter-alpha (globulin) inhibitor H3 4.975 0.013 0.019 Extracellular matrix stabilization
NM_002291 LAMB1 Laminin, beta 1 1.633 0.037 0.041 Cell adhesion, differentiation and migration
NM_005947 MT1B Metallothionein 1B 6.818 0.000 0.000 Bind heavy metals
NM_000607 ORM1 Orosomucoid 1 2.699 0.000 0.000 Unknown but suspected to be linked to immunosuppression
NM_001145031 PLAU Plasminogen activator, urokinase 2.348 0.032 0.037 Degradation of the extracellular matrix
NM_006622 PLK2 Polo-like kinase 2 2.320 0.000 0.000 Regulation cell cycle progression, mitosis, cytokinesis, and DNA damage response
NM_031310 PLVAP Plasmalemma vesicle associated protein 1.804 0.000 0.000 Formation of stomatal, microvascular permeability and fenestral diaphragms
NM_015869 PPARG Peroxisome proliferator-activated receptor gamma 2.501 0.010 0.015 Regulation of adipocyte differentiation
NM_012212 PTGR1 Prostaglandin reductase 1 1.629 0.023 0.029 Inactivation of the chemotactic factor, leukotriene B4
NM_021033 RAP2A RAP2A, member of RAS oncogene family 2.110 0.031 0.036 GTPase activity
NM_001085 SERPINA3 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.509 0.031 0.036 Plasma protease inhibitor
NM_012339 TSPAN15 Tetraspanin 15 4.210 0.000 0.000 Regulation of cell development, activation, growth and motility