Table 1. LOXL1 SNPs genotype and allele frequencies in PEXG patients and controls.
| rs1048661 G/T | Controls n=180 (%) | PEXG n=128 (%) | p-value | p-value | OR (95% CI) |
|---|---|---|---|---|---|
| GG |
78 (43.3) |
91 (71.1) |
0.00000064 |
||
| GT |
81 (45.0) |
36 (28.1) |
0.0001 |
2.63 (1.55–4.45) |
|
| TT |
21 (11.7) |
1 (0.80) |
0.00001 |
24.50 (3.37–500) |
|
|
Alleles | |||||
| G |
237 (65.8) |
218 (85.2) |
0.0000001 |
2.98 (1.94–4.57) |
|
| T |
123 (34.2) |
38 (14.8) |
|||
|
rs3825942 G/A |
Controls n=180 (%) |
PEXG n=128 (%) |
p-value |
p-value |
OR (95% CI) |
| GG |
130 (72.2) |
121 (94.5) |
0.000003 |
||
| GA |
42 (23.3) |
7 (5.50) |
0.00001 |
5.58 (2.30–14.19) |
|
| AA |
8 (4.5) |
0 (0.00) |
0.007 |
(N/A) |
|
|
Alleles | |||||
| G |
302 (83.90) |
249 (97.3) |
0.0000001 | 6.83 (2.94–16.67) | |
| A | 58 (16.10) | 7 (2.70) | |||