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. Author manuscript; available in PMC: 2013 May 11.
Published in final edited form as: Biochem Biophys Res Commun. 2012 Mar 24;421(3):413–417. doi: 10.1016/j.bbrc.2012.03.096

Figure 3.

Figure 3

Binding affinities of compounds 1 and 2. Binding affinity values in kcal/mol (y-axis) are plotted for compounds 1 (black bars) and 2 (white bars) against Plasmepsin-II (PLM-II), wild type (NL4-3) and MDR 769 HIV-1 protease receptors. 1 and 2 show equal or better binding affinity values against the NL4-3 receptor compared to their corresponding PLM-II models. The MDR 769 HIV-1 protease models show loss (>2 kcal/mol) of binding affinity for both compounds.