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. Author manuscript; available in PMC: 2013 Apr 30.

Published in final edited form as: J Control Release. 2012 Jan 24;159(2):232–239. doi: 10.1016/j.jconrel.2012.01.012

Fig. 2 — Visual assessment of polyplex stability in injection buffer (5% glucose) (A) and cell medium containing 10% serum (B) – conditions that mimic the in vivo fluid environment. Whereas PEI and PAEM polyplexes experienced much aggregation over time, PEGylated polyplexes remained stable without visible aggregation. Agarose gel electrophoresis of naked DNA and polyplexes before and after incubation in serum-containing medium (C) confirmed the absence of any free, unbound DNA. Scale bar: 100 μm.

Fig. 2 — Visual assessment of polyplex stability in injection buffer (5% glucose) (A) and cell medium containing 10% serum (B) – conditions that mimic the in vivo fluid environment. Whereas PEI and PAEM polyplexes experienced much aggregation over time, PEGylated polyplexes remained stable without visible aggregation. Agarose gel electrophoresis of naked DNA and polyplexes before and after incubation in serum-containing medium (C) confirmed the absence of any free, unbound DNA. Scale bar: 100 μm.