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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Neuroimage. 2011 Dec 7;61(2):505–516. doi: 10.1016/j.neuroimage.2011.11.075

Figure 1.

Figure 1

Volumetric MRI in the the detection and tracking of AD, including (i) accelerated rates of atrophy in the hippocampus (Hi) and entorhinal cortex (ERC) regions-of-interest (Mike Weiner, with permission); (ii) accelerated rates of whole brain atrophy using sequential MRIs, as shown in red in a symptomatic AD patient (Nick Fox, with permission); (iii) regional gray matter loss, as shown in this statistical brain map comparing symptomatic AD patients and controls. Reprinted from (Baron et al., 2001), Copyright © 2001 with permission from Elsevier. All rights reserved; and (iv) regional thinning in cerebral cortex, as shown in this statistical brain map comparing symptomatic AD patients and controls. Reprinted with permission from (Du et al., 2007), Copyright © 2007 Oxford University Press. All rights reserved. This figure was reproduced with permission from (Reiman and Langbaum, 2009), Copyright © 2009 Oxford University Press. All rights reserved.