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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Oct 13;1822(7):1169–1179. doi: 10.1016/j.bbadis.2011.10.007

Fig. 3.

Fig. 3

ABCA4 deficiency does not increase retinal degeneration up to P120. Measuring from the optic nerve head, sections (as in Fig. 2) were imaged at 100 μm intervals. Total nuclei in the ONL were counted in each image from 3 to 5 mice per group. Values are presented as mean±SEM. Horizontal gray lines represent average levels at P30. (A) WT mice and their ABCA4 deficient counterparts do not exhibit any retinal thinning up to P120 at either light level. (B) In the Nrl−/− background, a decrease in ONL thickness is observed by P120 but neither lack of ABCA4 nor light exposure has any significant effect on the decrease. N: nasal, T: temporal.