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. Author manuscript; available in PMC: 2013 Jul 20.
Published in final edited form as: J Control Release. 2012 Jan 21;161(2):338–350. doi: 10.1016/j.jconrel.2012.01.018

Figure 3.

Figure 3

A) Chemical structure of the sulfonate-modified polyvinyl alcohol hydrogel polymer used in the fabrication of DC Bead. B) and C) Demonstration of the ionic interaction between the sulfonate groups in DEB (see dashed circle in A) with doxorubicin (B) or irinotecan (C) using Fourier Transform Infrared Microscopy. Note the shift in the position of the S=O stretching absorption from higher to lower wavenumber with increasing concentration of drug bound within the system, denoting a shift from free to bound S=O groups. B and C courtesy of Dr. J. Namur.