Table 7.
Sleep efficiency (%) in randomized controlled trials of APAP versus CPAP
| Study PMID |
Baseline AHI (SD) [eligibility] |
Baseline ESS (SD) | Duration (design) | Interventions | Number analyzed | Baseline (SD) | Change (final) |
Net difference or difference |
95% CI | P | Dropout (%) | Study quality |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Konermann 1998 [31] 9515848 |
38 (14) [> 20} |
nd | 3 to 6 months (PL) |
APAP | 25 | 94.5 (5.4) | 2 | 6 | nd | NS | 4 | B |
| CPAP | 23 | 89.2 (13.7) |
-4 | |||||||||
| Nolan 2007 [14] 17326544 |
15 (8) [≥5) |
12.3 (4) | 2 months (PL) |
APAP | 29 | 79 (9) | 4 | -1 | -4.3 to 2.3a | 0.39 | 15 | B |
| CPAP | 29 | 79 (9) | 5 | |||||||||
| Resta 2004 [24] 15679008 |
47 (11) [> 30] |
13.9 (3.2) | 1 month (PL) |
APAP | 10 | 86.9 (8) |
-0.5 | -2.5 | nd | nd | 0 | C |
| CPAP | 10 | 84.2 (4.9) |
2 |
AHI: apnea-hypopnea index (events/hour); APAP: auto-titrating CPAP; CPAP: continuous positive airway pressure; ESS: Epworth Sleepiness Scale; nd: no data; NS: non-significant; PL = parallel design. aEstimated from reported data.