Table 2.
Results of primary meta-analyses and sensitivity analyses
| Intervention outcome pairing | Primary analysis main effect, (95% CI); N trials; I2 (%) | Sensitivity analysis main effect, (95% CI); N trials; I2 (%) |
|---|---|---|
| Hypericum perforatum-HAM-D | WMD = -3.43 (-4.6 to -2.25); 22ab; I2 = 84.7% | WMD = -3.61 (-4.14 to -3.07); 13ab; I2 = 87.7% |
| Allium sativum-TC | WMD = -8.95 (-9.65 to -8.25); 25ab; I2 = 99.1% | WMD = -9.27 (-9.98 to -8.56); 19ab; I2 = 99.3% |
| Allium sativum-LDL | WMD = -4.99 (-5.4 to -4.59); 20ab; I2 = 65.7% | WMD = -5.05 (-5.45 to -4.64); 13ab; I2 = 96.4% |
| Allium sativum-HDL | WMD = 1.15 (1.05 to 1.25); 21ab; I2 = 77.7% | WMD = 1.15 (1.05 to 1.25); 11ab; I2 = 86.4% |
| Allium sativum-TG | WMD = -15.78 (-17.30 to -14.24); 22ab; I2 = 98.4% | WMD = -15.72 (-17.34 to -14.09); 10ab; I2 = 99.2% |
aP < 0.001 for the main effect.
bP < 0.001 for Cochran's Q test.
HAM-D = Hamilton Depression Scale score; HDL = high-density lipoprotein; LDL = low-density lipoprotein; TC = total cholesterol; TG = triglyceride; WMD = weighted mean differences.