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The immunohistochemical staining of proliferating cell nuclear antigen Ki-067 after mesenchymal stem cells transplantation at 6 h (A, B), 24 h (C, D) and 72 h (E, F). Cell proliferation (brown cells) was obvious. The number of stained (brown) cells in the severe acute pancreatitis (SAP) + mesenchymal stem cells group (B, D, F) were significantly higher than the SAP group. Cell numbers gradually increased with time (original magnification × 400).
