Photomicrograph of CCOT lining epithelium and ghost cells demonstrating Notch receptor proteins: A and B, Notch1: positive expression was observed in both ghost cells and tumoral epithelium; C, Notch2: all lesional components were negative; D, Notch3: weak to negative labeling of tumoral tissues. Note strong Notch3 positivity in stromal blood vessels. (A, ×100, B-D, ×200).