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. 2012 Jun;53(6):1080–1092. doi: 10.1194/jlr.M023382

TABLE 3.

Hepatic acylcarnitine levels in overnight-fasted mice on a high-fat diet

8 Weeks
16 Weeks
32 Weeks
Control Diet HFD P Control Diet HFD P Control Diet HFD P
Free carnitine 1337 ± 91 1680 ± 260 0.17 1555 ± 65 1374 ± 144 0.13 1345 ± 223 1384 ± 151 0.44
 C2 5.33 ± 1.4 6.74 ± 1.2 0.22 8.67 ± 1.2 13.2 ± 3.6 0.15 6.52 ± 1.7 26.5 ± 10 0.05
 C3 3.75 ± 0.69 12.3 ± 5.1 0.07 8.93 ± 2.1 11.5 ± 4.05 0.29 2.16 ± 0.40 12.8 ± 2.9 0.006
 C4 2.99 ± 1.0 2.79 ± 0.77 0.43 1.43 ± 0.18 4.23 ± 1.9 0.10 3.95 ± 0.66 12.0 ± 3.0 0.02
 C5 0.25 ± 0.06 0.24 ± 0.04 0.43 0.28 ± 0.05 0.37 ± 0.06 0.29 1.37 ± 0.18 2.14 ± 0.23 0.01
 C14 0.08 ± 0.02 0.04 ± 0.01 0.06 0.05 ± 0.01 0.05 ± 0.01 0.45 0.04 ± 0.004 0.06 ± 0.01 0.07
 C16 0.49 ± 0.06 0.68 ± 0.2 0.20 0.34 ± 0.06 0.52 ± 0.12 0.18 0.52 ± 0.05 0.75 ± 0.1 0.04

Acylcarnitine (nmol/g protein) in liver. Data are represented as the mean ± SE (n = 6–8).