TABLE 1.
Body weight gain, food intake, and relative adipose depot masses corrected for body weight of rats treated with rapamycin (Rapa) and/or rosiglitazone (RSG) for 15 days
Control | Rapa | RSG | Rapa + RSG | |
Body weight gain (g) | 98.3 ± 2.7a | 12.6 ± 2.3b | 111.2 ± 2.7c | 9.61 ± 3.0b |
Food intake (g) | 214 ± 9.6a | 179 ± 10.1b | 242 ± 12.0a | 167 ± 8.6b |
Food efficiencyd (%) | 65.3 ± 1.2a | 11.6 ± 2.3b | 71.6 ± 2.1a | 13.6 ± 2.6b |
Retroperitoneal fat (%) | 0.87 ± 0.05a | 0.53 ± 0.04b | 0.84 ± 0.05a | 0.79 ± 0.04a |
Inguinal fat (%) | 1.06 ± 0.08a | 0.90 ± 0.04a | 1.58 ± 0.06b | 1.26 ± 0.04c |
Brown fat (%) | 0.09 ± 0.01a | 0.08 ± 0.01a | 0.33 ± 0.02b | 0.18 ± 0.02c |
Adiponectin (μg/ml) | 2.44 ± 0.25a | 3.17 ± 0.28a | 9.38 ± 1.01b | 6.66 ± 1.45c |
Data are average ± SE, n = 12–20 rats. All groups had the same average body weight (230 g) at the onset of treatments.
Means not sharing a common superscript are significantly different from each other, P < 0.05.
Calculated as grams of body weight gain per 100 g of food ingested.