Fig. 6.
LXRα and LXRβ exhibit comparable ability to control inflammatory gene expression in macrophages. Thioglycollate-elicited peritoneal macrophages from E KO, E/α KO and E/β KO mice were treated for 24 h with 1 μmol/L GW3965 then stimulate with LPS (100 nM) for 4 h. Gene expression of inflammatory genes was examined by real-time PCR.