Table 1.
Antimicrobial susceptibilities of 6 epidemic Burkholderia cepacia complex isolates (P-5, P-6, P-7. P-8. and P-9) in the NICU and 2 isolates (P-a and P-B) from unrelated wards with the neg combo 3.12J panels with the MicroScan Walkaway 40 System
| Patient No.# | Date of Isolation day/month/year | Specimen Obtained | MIC(μg/ml) | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PIPC | CAZ | CFS | CFPM | CZOP | AZT | IPM | MEPM | TOB | AMK | GM | MINO | LVFX | CPFX | ST | FOM | C/S | P/T | |||
| P-A | 07/09/2010 | bronchial aspirate | > 64 | > 16 | > 16 | > 16 | > 16 | > 16 | > 8 | < 1 | > 8 | > 32 | > 8 | < 2 | 2 | 2 | < 2 | > 16 | > 32 | < 8 |
| P-B | 13/09/2010 | salivary fluid | 64 | 4 | > 16 | > 16 | > 16 | > 16 | > 8 | 2 | > 8 | > 32 | > 8 | 4 | 4 | > 2 | > 2 | > 16 | > 32 | < 8 |
| P-5 | 14/09/2010 | bronchial aspirate | > 64 | 4 | > 16 | > 16 | > 16 | > 16 | > 8 | < 1 | > 8 | > 32 | > 8 | < 2 | 1 | 1 | < 2 | > 16 | > 32 | < 8 |
| P-6a | 21/09/2010 | peripheral blood | > 64 | 4 | > 16 | > 16 | > 16 | > 16 | 8 | < 1 | > 8 | > 32 | > 8 | < 2 | 1 | 1 | < 2 | > 16 | > 32 | < 8 |
| P-6b | 12/10/2010 | catheterized urine | > 64 | 8 | > 16 | > 16 | > 16 | > 16 | 8 | < 1 | > 8 | > 32 | > 8 | < 2 | 1 | 1 | < 2 | > 16 | > 32 | < 8 |
| P-7 | 14/09/2010 | bronchial aspirate | 64 | 8 | > 16 | > 16 | > 16 | > 16 | > 8 | < 1 | > 8 | > 32 | > 8 | < 2 | 1 | 1 | < 2 | > 16 | > 32 | < 8 |
| P-8 | 28/09/2010 | bronchial aspirate | > 64 | 4 | > 16 | > 16 | > 16 | > 16 | 8 | < 1 | > 8 | > 32 | > 8 | < 2 | 1 | 1 | < 2 | > 16 | > 32 | < 8 |
| P-9 | 18/01/2011 | bronchial aspirate | 64 | 8 | > 16 | > 16 | > 16 | > 16 | 8 | < 1 | > 8 | > 32 | > 8 | < 2 | < 0.5 | 0.5 | < 2 | > 16 | > 32 | < 8 |
PIPC: piperacillin, CAZ: ceftazidime, CFS: cefsulodin, CFPM: cefepime, CZOP: cefozopran, AZT: aztreonam, IPM: imipenem, MEPM: meropenem, TOB: tobramycin AMK: amikacin, GM: gentamicin, MINO: minocycline, LVFX: levofloxacin,, CPFX: ciprofloxacin, ST: sulfamethoxazole/trimethoprim, FOM: fosfomycin, C/S: cefoperazone/sulbactam, P/T: piperacillin/tazobactam #: P-A: Patient a, P-B: Patient B, both hospitalized in different wards unrelated to the NICU. as for P-5, -6, -7, -8, and -9, see text in the Results section, for the backgrounds of the isolates.