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. 2009 Sep 1;14(9):378–392. doi: 10.1186/2047-783X-14-9-378

Table 1.

Characteristics of IRCU patients with low and high N-Alb-P excretion in fasting urine (A), absence or presence of renal stones in situ (B), and of all patients (C)

A. N-Alb-P; median
Low
4.3 mg
High
High vs. Low B. Stones
Absent
Present C. All
Present vs. Absent
Mean Range Normal1
N+ ≤Median >Median p p
Urine
Total protein; mg 187 3.3 (0.2); 94 13 (2); 93++ < 0.001x 6.2 (0.5); 94++ 9.7 (2.1); 93++ 0.24x 7.93 0.8-161 < 50
N-Alb-P; mg 187 1.7 (0.4); 94++ 11 (1.9); 93 < 0.001x 5.1 (0.4); 94 7.3 (2.1); 93 0.19x 6.19 0-161 < 7.0
Cr*-Clearance; ml/min 187 108 (2); 94 115 (3); 93 0.03 112 (3); 94 111 (2); 93 0.44 111 41-187 > 50
103 × FE-N-Alb-P; % 187 0.90 (0.0); 94 3.4 (0.5); 93 < 0.001 1.8 (0.0); 94 2.7 (0.0); 93 0.13x 2.2 0.08-45
Volume; ml 187 161 (11); 94 290 (17); 93 < 0.001 229 (15); 94 221 (16); 93 0.25x 225 60-720 50-600
Na; mM 187 10 (0.4); 94 15 (0.8); 93 < 0.001 13 (0.6); 94 12 (0.7); 93 0.43 12.5 2-47 < 20
K; mM 187 6.7 (0.2); 94 9.0 (0.3); 93 < 0.001 7.8 (0.3); 94 7.9 (0.3); 93 0.41 7.8 1.8-17 2-8
Ca; μM 187 298 (19); 93 334 (16); 94 0.07x 307 (17); 94 325 (18); 93 0.23x 316 29-1261 < 625
Mg; μM 187 231 (10); 94 277 (10); 93 0.002 257 (10); 93 250 (12); 94 0.34 253 48-776 > 280
Pi; mM 187 1.15 (0.06); 94 1.23 (0.07); 93 0.22x 1.19 (0.06); 94 1.19 (0.07); 93 0.47x 1.19 0.10-3.9 < 3
Ox; μM 179 22 (1.4); 88 23 (2.1); 91 0.34 23 (1); 89 24 (2); 90 0.32 22 1.3-193 < 37
Cit; μM 185 253 (13); 93 311 (14); 92 0.001 290 (14); 93 272 (13); 92 0.16 279 44-732 > 132
pH 187 5.92 (0.09); 94 6.35 (0.07); 93 < 0.001 5.95 (0.08); 94 6.33 (0.07); 93 < 0.001 6.14 4.4-7.6 5.2-7.9
General features
Age; y 187 42 (1.2); 94 41 (1.2); 93 0.25 41 (1.2); 94 42 (1.2); 93 0.29 41.6 21-67 > 22
ASFP; score 187 35 (4); 94 40 (4); 93 0.18 x 34 (4); 94 41 (4); 93 0.08x 36 1-271 1
Renal stones; Absent/Present 187 47/47; 94 46/47; 93 94/0 0/93
Systolic blood pressure; mmHg 152 126 (2); 78 132 (3); 74 0.004 129 (2); 75 129 (3); 77 0.44 129 90-220 ≤130
Diastolic blood pressure; mmHg 152 82 (1); 78 86 (2); 74 0.03 83 (1); 75 84 (2); 77 0.32 84 60-150 ≤80
BMI; kg/(m)2 187 26.4 (0.3); 94 26.2 (0.4); 93 0.39 26.2 (0.3); 94 26.5 (0.4); 94 0.25 26.3 19-40 ≤25
P**-Insulin; μU/ml 184 17 (1); 92 16 (1); 92 0.26 16 (1); 91 17 (1); 93 0.36 16 1-83 < 20
P-K; mM/l 106 4.2 (0.03); 62 4.2 (0.05);44 0.46 4.2 (0.04); 49 4.2 (0.04); 57 0.43 4.2 3.6-5.1 3.8-5.0
U**-Hypoxanthine; μM 75 9.9 (0.8); 29 13 (0.7); 46 < 0.001x 11.5 (0.8); 39 12.7 (0.8); 36 0.08x 12.1 2.8-25 < 30
U-Xanthine; μM 75 4.0 (0.4); 29 7.8 (0.5); 46 < 0.001x 6.4 (0.6); 39 6.3 (0.5); 36 0.45x 6.3 1.2-17 > 3
U-Uric acid; μM 187 357 (16); 94 433 (14); 93 < 0.001 403 (12); 94 386 (18); 93 0.21x 395 44-1351 < 400
U-FE-Uric acid; % 186 7.4 (0.3); 94 8.8 (0.4); 92 < 0.001 8.3 (0.3); 94 7.8 (0.4); 92 0.16 8.1 0.7-24 < 11
P-Uric acid; μM/l 187 374 (7); 94 342 (7); 93 < 0.001 353 (7); 94 363 (7); 93 0.17 358 160-631 < 446
P-TAS; mM/l 57 1.37 (0.02); 21 1.31 (0.01); 36 0.007 1.34 (0.02); 30 1.32 (0.02); 27 0.20 1.33 1.18-1.49 1.29-1.61
U-MDA; nM 176 116 (5); 89 148 (7); 87 < 0.001 135 (6); 88 129 (6); 88 0.24 132 25-345 < 110
U-MDA/P-Uric acid; nM/mM × l -1 176 316 (14); 89 486 (22); 87 < 0.001x 373 (20); 88 397 (20); 88 0.19x 385 74-1051 < 375

All excretions ratesare per 2 h. If not otherwise indicated, data are mean values (SE). For further informations see text.

+: total number of patients; ++: number of patients in subgroups; *: creatinine; **: U and P indicate urine and plasma, respectively; x: based on log10; nd: not determined; 1: limits or range observed in 10 - 20 healthy adult male subjects in the authors' laboratory, and from literature.