Table 1.
Clinical characteristics and genotype distribution in patients with aseptic loosening
| All | BCL-2 genotype | p-value | |||
|---|---|---|---|---|---|
| CC | CA | AA | |||
| n (%) | 87 | 22 (25.28) | 49 (56.32) | 16 (18.4) | |
| Age at implantation (y) | 60.18 ± 13.14 | 58.14 ± 14.06 | 60.94 ± 13.72 | 60.69 ± 10.08 | 0.703 |
| Age at replantation (y) | 69.31 ± 10.27 | 67.41 ± 12.77 | 70.04 ± 9.81 | 69.69 ± 7.79 | 0.605 |
| Gender | |||||
| Female (%) | 60 (68.97) | 12 (20.0) | 35 (58.33) | 13 (21.66) | 0.182 |
| Male (%) | 27 (31.03) | 10 (37.04) | 14 (51.86) | 3 (0.11) | |
| Weight (kg) | 75.11 ± 17.11 | 75.88 ± 19.59 | 76.1 ± 16.65 | 71.13 ± 15.18 | 0.592 |
| Height (cm) | 166.80 ± 8.35 | 168.09 ± 6.91 | 166.77 ± 9.13 | 165.13 ± 7.95 | 0.563 |
| BMI (kg/m_) | 26.86 ± 5.07 | 26.74 ± 6.04 | 27.25 ± 4.92 | 25.9 ± 4.15 | 0.655 |
| First cup with cement (n = 83) | |||||
| no | 34 (40.96) | 6 (17.65) | 19 (55.88) | 9 (26.47) | 0.280 |
| yes | 49 (59.04) | 14 (28.57) | 28 (57.14) | 7 (14.29) | |
| First stem with cement (n = 80) | |||||
| no | 30 (37.5) | 4 (13.33) | 19 (63.33) | 7 (23.33) | 0.147 |
| yes | 50 (62.5) | 16 (32.0) | 27 (54.0) | 7 (14.0) | |
| Acetabular defects (Paprosky) n = 60 | |||||
| I | 6 (10) | 3 (50.0) | 2 (33.33) | 1 (16.66) | 0.479 |
| II | 23 (38.83) | 5 (21.74) | 12 (52.17) | 3 (13.04) | |
| III | 31 (51.66) | 7 (22.58) | 17 (54.84) | 7 (22.58) | |
| Femoral defects (Paprosky) n = 52 | |||||
| 1 | 4 (7.69) | 4 (100) | 0 | 0 | 0.377 |
| 2 | 23 (44.23) | 5 (21.74) | 14 (60.87) | 4 (17.39) | |
| 3 | 25 (48.08) | 8 (32.0) | 12 (48.0) | 5 (20.0) | |
Data are numbers with percentages given in brackets and numbers with standard deviation, respectively. Categorical variables were analyzed by χ2 statistics. P values were calculated using ANOVA for continuous variables.