Table 1.
Characteristics of HIV controllers, non-controllers, and HAART suppressors
| Characteristic | Elite Controllers | Viremic Controllers | HIV Controllers | Non- Controllers | P-value HIV Controllers vs. Non- controllers |
HAART Suppressors | P-value HIV Controllers vs. HAART Suppressors |
|---|---|---|---|---|---|---|---|
| Number of Participants, n | 33 | 116 | 149 | 3822 | - | 491 | - |
| Age at HIV Diagnosis (years) | 29.3 ± 7.4 | 28.8 ± 6.6 | 28.9 ± 6.8 | 29.4 ± 7.8 | 0.45 | 31.1 ± 7.9 | 0.002 |
| Gender, Male | 30 (90.9) | 102 (87.9) | 132 (88.6) | 3512 (91.9) | 0.15 | 450 (91.6) | 0.25 |
| Race/Ethnicity | |||||||
| European American | 12 (36.4) | 41 (35.3) | 53 (35.6) | 1725 (45.2) | 0.021 | 244 (49.7) | 0.002 |
| African American | 21 (63.6) | 64 (55.2) | 85 (57.0) | 1668 (43.7) | 0.001 | 192 (39.1) | < 0.001 |
| Hispanic | 0 (0.0) | 6 (5.2) | 6 (4.0) | 300 (7.9) | 0.09 | 38 (7.7) | 0.12 |
| Other | 0 (0.0) | 5 (4.3) | 5 (3.4) | 127 (3.4) | 0.98 | 17 (3.5) | 0.95 |
| Year of HIV Diagnosis | 1993 ± 6 | 1995 ± 6 | 1995 ± 6 | 1991 ± 5 | < 0.001 | 1995 ± 5 | 0.90 |
| Mean CD4+ Count at HIV Diagnosis (cells/uL) | 689.7 ± 241.6 | 731.9 ± 232.6 | 723.4 ± 234.0 | 539.2 ± 275.1 | < 0.001 | 504.7 ± 242.6 | < 0.001 |
| Mean Viral Load at HIV Diagnosis (log10 copies/mL) | 2.7 ± 0.8 | 3.0 ± 0.8 | 3.0 ± 0.8 | 4.3 ± 0.8 | < 0.001 | 4.4 ± 0.8 | < 0.001 |
| Year of First DTH Testa | 1997 ± 4 | 1997 ± 5 | 1997 ± 5 | 1992 ± 5 | < 0.001 | 2000 ± 2 | < 0.001 |
| Mean Number of DTH Testing Episodes | 4.9 ± 4.2 | 5.7 ± 5.0 | 5.5 ± 4.8 | 5.5 ± 4.7 | 0.84 | N/A | N/A |
NOTE. HIV controllers, combined group of elite and viremic controllers; HAART suppressors, subgroup of non-controllers on suppressive HAART; all values are number, percent or SD unless otherwise specified
a First DTH for HAART subgroup defined as first DTH test 2 years after start of initial HAART regimen