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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Arch Toxicol. 2011 Apr 27;85(9):1015–1033. doi: 10.1007/s00204-011-0705-2

Figure 6.

Figure 6

The Regulation Summary Diagram, which includes elements such as other genes in the same transcription unit, the sigma factor involved in transcription, the gene product and complexes formed by it, and different regulators that control transcription, translation, and activity. This example, which describes the trpA gene of Escherichia coli, includes the TrpR transcriptional regulator and the compound tryptophan (which also functions as a transcription regulator), a small RNA molecule that regulates translation of the mRNA, and the compound pyridoxal phosphate that activates the enzyme.