Table 3.
GEE results from family-based validation dataset (n = 2,564, 755 affected and 1,809 unaffected individuals)
| Parameter | Z PR | P value | OR | Lower limit | Upper limit | |
|---|---|---|---|---|---|---|
| GABBR2_1a | ||||||
| Deletion | 0.3100 | 0.7582 | 1.14 | 0.500 | 2.587 | |
| Duplication | -2.1800 | 0.0292 | 0.72 | 0.542 | 0.968 | |
| Event | -1.9800 | 0.0476 | 0.76 | 0.579 | 0.997 | |
| NRXN1_1a | ||||||
| Deletion | 2.3000 | 0.0215 | 2.75 | 1.161 | 6.508 | |
| Duplication | 1.1500 | 0.2515 | 3.24 | 0.435 | 24.085 | |
| Event | 2.5300 | 0.0114 | 2.81 | 1.262 | 6.258 | |
| NRXN1_2a | ||||||
| Deletion | 2.1400 | 0.0320 | 2.33 | 1.075 | 5.059 | |
| Duplication | -0.9700 | 0.3309 | 0.34 | 0.040 | 2.963 | |
| Event | 0.8500 | 0.3959 | 1.40 | 0.644 | 3.040 |
aContains deletion or duplication significant at P < 0.05. Only loci demonstrating statistical significance are shown here.