Figure 2.
Subcutaneous morphine induces GFAP mRNA expression in DRGs but not in spinal cords. (A, B) Real-time RT-PCR showing the time course of GFAP expression in lumbar DRGs (A) and spinal cord dorsal horns (B) after subcutaneous morphine injection (10 mg/kg, s.c.). Note that acute morphine only increases GFAP mRNA expression in DRGs but not in spinal cord dorsal horns. The data are expressed as fold of naïve controls. *P < 0.05, vs. control, ANOVA followed by Bonferroni post hoc test, n = 4 mice.