Table 1.
Comparison of demographic and serological parameters used in this study
| Parameter | CF (n = 119) | CD (n = 34) | UC (n = 11) | RA (n = 22) | HC (n = 16) | p < 0.05 |
|---|---|---|---|---|---|---|
| Gender (m/f) | 67/52 | 14/20 | 3/8 | 5/17 | 10/6 | n.s. |
| Age | 23.0 | 36.5 | 30.0 | 57.5 | 29.0 | RA vs. all |
| (years) | [16, 33]* | [29, 58] | [25, 61] | [49, 64] | [28, 34] | |
| WBC | 8.9 | 8.5 | 8.5 | 8.0 | n.d. | n.s. |
| (/nl) | [7, 11] | [5, 10] | [6, 11] | [6, 11] | ||
| CRP | 0.3 | 0.4 | 0.3 | 0.3 | n.d. | n.s. |
| (mg/dl) | [0.1, 1.0] | [0.1, 1.2] | [0.05, 1,0] | [0.1, 3.9] | ||
| ALCA | 18.8 | 30.8 | 16.3 | 14.3 | 23.3 | CD vs. RA |
| (U/ml) | [12, 32] | [21, 50] | [12, 29] | [9, 20] | [19, 31] | |
| ACCA | 22.2 | 35.4 | 30 | 24.1 | 35.6 | n.s. |
| (U/ml) | [17, 39] | [22, 47] | [16, 40] | [17, 31] | [27, 42] | |
| AMCA | 29.9 | 32.8 | 23.1 | 23.8 | 30.6 | n.s. |
| (U/ml) | [23, 46] | [25, 55] | [16, 26] | [20, 30] | [20, 40] | |
| gASCA | 55.6 | 88.9 | 20.5 | 20.0 | 23.0 | CD vs. |
| (U/ml) | [27, 124] | [51, 14.3] | [15, 40] | [14, 27] | [10, 38] | CU, RA, HC |
Continuous variables: median [Q25%, Q75%], WBC = white blood cell count; CRP = C-reactive protein; CF = cystic fibrosis; CD = Crohn's disease; UC = ulcerative colitis; RA = rheumatoid arthritis; HC = healthy volunteers. Differences between groups were compared by ANOVA with Scheffe-Test or Fisher's exact test(*) with Bonferroni.