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Performance characteristics of anti-glycan antibodies for detection of patients with Crohn's disease
| SE | SP | PPV | NPV | ACC | |
|---|---|---|---|---|---|
| gASCA only | 76.5 | 91.8 | 86.7 | 84.9 | 85.5 |
| gASCA+1Ab | 41.2 | 95.9 | 87.5 | 70.1 | 73.5 |
| gASCA+2Ab | 17.6 | 100 | 100.0 | 63.6 | 66.3 |
| gASCA+3Ab | 2.9 | 100 | 100.0 | 59.8 | 60.2 |
SE = sensitivity; SP = specificity; PPV = positive predictive value; NPV = negative predictive value; ACC = accuracy; Ab anti-glycan antibodies (ACCA, ALCA, AMCA). Sera positive antibody titers were defined as ≥ 50 U/ml.
